The OncoFirm Platform

One reader. One strip design. A growing menu of tests.

OncoFirm's fluorescent lateral-flow platform was built first for cancer antigens such as CEA and PSA. The same strip format, handheld reader and software are designed to carry tests for sexually transmitted and respiratory infections, pregnancy and fertility, and heart, lung and blood conditions.

OncoFirm handheld fluorescence reader showing a test result, next to an OncoFirm test cassette
Design rendering of the OncoFirm handheld reader and test cassette. The reader measures how brightly the test line glows and reports a number.
Readout: quantitative, in unitsResult time target: ≤ 20 min
Conditions at a glance

What the platform is designed to test for

  • Cancer
  • Chlamydia
  • Gonorrhea
  • Syphilis
  • Hepatitis B
  • Hepatitis C
  • HIV
  • H. pylori
  • Influenza
  • COVID-19
  • RSV
  • Strep
  • Legionella
  • Mono
  • Lyme disease
  • Pregnancy and fertility
  • Heart
  • Lung
  • Blood
  • Inflammation
Sample to result

Three steps, the same for every test

01

Add a small sample

A drop of blood, a little urine, a swab or a stool sample, depending on the test.

02

Insert into the reader

The reader scans the full fluorescence profile and checks that the test ran correctly.

4.2 03

Get a number, logged

A quantitative result in minutes, saved to a traceable record without retyping.

How it works

Four parts that work the same for every test

SAMPLE TEST REFERENCE CONTROL sample flow → reader scans the full strip profile
Every strip carries a fluorescent reference line of known quantity, so each test checks its own calibration.
Stays the same for every new test
  • Reader hardware and optics
  • Strip format and reference line
  • Signal analysis and quality checks
  • Data format and reporting
Changes for each new test
  • The antibody or antigen pair for the new target
  • Its calibration settings

Fluorescent test strip

Antibodies labeled with bright fluorescent reporters capture the target in a small sample.

Built-in reference

A reference line of known fluorescence sits beside the test line, so lot, temperature and handling effects are corrected inside each test.

Handheld reader

The reader records the full fluorescence profile across the strip, not just a single spot, and flags tests that did not run correctly.

Software and data

AI-assisted analysis turns the profile into a numeric result, and cloud-enabled records keep results traceable across sites.

Infectious disease

Infectious disease tests the platform is designed to carry

Rapid infectious disease testing is where lateral flow proved itself. OncoFirm adds a quantitative, self-checking reader and connected data to that format.

Bloodborne and sexually transmitted infections

Blood, serum or swab samples. The STI tests make up the planned inSTIcheck™ line.

Respiratory and throat infections

Nasal, throat or urine samples, or a fingerstick for mono.

Stomach and tick-borne infections

Stool or blood samples.

Beyond infection

Cancer, pregnancy and fertility, heart, lung and blood

Sample types vary by test: blood, serum or plasma, urine, swab or stool.

Experience

Experience with infectious disease rapid tests

Before founding OncoFirm, our CEO, Jonathan Adam Barash, worked at First Diagnostic Corporation on hepatitis B (HBsAg) and hepatitis C rapid tests that were recommended by the U.S. Army Medical Materiel Center–Europe (USAMMCE). OncoFirm brings that field experience to a new generation of quantitative, connected tests.

Development status. The OncoFirm platform and every test described on this page are in development. They have not been cleared or approved by the FDA and are not available for sale. Pictures are design renderings and illustrations, not photographs of finished products.

Partner with us

We are looking for research, clinical and distribution partners for the test menu. Tell us which test matters to your work.

[email protected]+1 516.900.2606Port Washington, NY